Offers “Roche”

Expires soon Roche

Biomarker Scientist_social computational neuroscience

  • Internship
  • Basel, SWITZERLAND

Job description



·  Job facts

At Roche, we believe it's urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients' lives and we are daring in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

This role is within the The Translational Technology team sits within Neuroscience and Rare Diseases (NRD), Pharma Research and early Development (pRED). The Biomarker Expert in Social/Affective Computational Neuroscience is placed in the Biomarkers & Translational Technology group in order to facilitate the design, implementation and execution of novel assays and analyses to accelerate the discovery of intervention for complex social/affective dysfunction in neurological and psychiatric conditions.

The successful candidate is expected to have demonstrated mastery of the integration of diverse neuroscientific techniques to quantitate social and affective behavior. Specifically, the successful candidate will have a proven track record of integrating genetic/transcriptomic data, cognitive/behavioral data, and/or neuroimaging or physiological data and bringing these fused data to bear on critical questions for intervention discovery.

Experience in experimental design and data collection with emerging technologies is also critical, including the use of crowdsourcing methods, smartphone or wearables, and/or virtual-reality based platforms.

Success in this role will require a keen understanding of the intersection between neurobiological, neuropsychological, and neurocomputational levels of analyses, and an ability to identify strategically relevant and tractable questions at this nexus. To this end the candidate will be expected to keep abreast of new developments in relevant literatures; to communicate and disseminate these advancements as appropriate within and beyond our group; to maintain a diverse network of internal and external collaborations; and to rigorously pioneer these techniques in Roche's experimental medicine and clinical trials.

Primary Accountabilities and Responsibilities

·  Stay abreast of emerging techniques relevant to social, affective and computational neuroscience, via regular review of peer-reviewed papers, preprints, attending relevant conferences, and membership in relevant working groups/consortia;
·  Demonstrated ability to empirically “bridge” traditionally-distinct levels of analyses in biomarker discovery, including from genomics to phenomics, from detailed neuronal microcircuits to macroscale neurofunctional dynamics; and from individual to population-level inference;
·  Experience with deploying such multimodal biomarkers in interventional trials;
·  Ability to identify and guide the strategic development of advanced quantitative methods for population stratification, to response or prognosis prediction, to establishing target engagement or pharmacodynamic activity, or to providing an early signal of efficacy;
·  Communicating the results of these analyses in the form of regular internal updates, periodic internal and external presentations and posters, and peer-reviewed publications at landmark achievements
·  Excellent timeline management, including providing clear timelines associated with these analyses, proactively identifying timeline risks, and taking efforts to mitigate these risks
·  Fairly and critically evaluate key precedents to your work, both internal and external, including a rigorous understanding of the risks of experimenter degrees of freedom, the importance of pre-registration, and the importance of error rate control in iterated research & development efforts

Your profile

·  Minimum: Ph.D. with Postdoctoral training, or equivalent, preferably in the field of Social Neuroscience and Pharmacology
·  Strong publication record in this area
·  Expertise in Matlab, R and/or Python with diverse computational approaches
·  Expertise in applying and analyzing state-of-the-art brain imaging and psychophysiological techniques (MRI, PET, MRS, EEG, eytracking etc.) in humans
·  Expertise in Social and Affective Neuroscience
·  Experience designing, running and interpreting human observation and intervention studies
·  Excellent oral and written communication skills
·  Ample experience with scientific writing and publishing in peer-reviewed journals
·  Strong presentation skills and track record of presentations at international conferences
·  Ensures communication is two-way; responds and acts on feedback.
·  Establishes & maintains good working relationships and is co-operative.
·  Familiarity with pre-registration tools including OSF.io or aspredicted.org is a plus

Are you ready to apply? We are looking a person who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities at Roche.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building teams that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions, then please check our FAQs and videos on careers.roche.ch/faq.

Roche is an equal opportunity employer.

·  Who we are

At Roche, 98,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.

Make every future a success.
  • Job directory
  • Business directory