BIOTECHNICIAN, ASSOCIATE SCIENTIST NONCLINICAL SAFETY HF

Job description

BELGIQUE(Beerse)
du01 août 2020au01 août 2022(pour24mois)
ETABLISSEMENT :JANSSEN-CILAG
REMUNERATION MENSUELLE :1809€ (indemnité non contractuelle fixée par décret et arrêté, dont le montant peut varier notamment en
fonction de l’évolution du barème de référence, de la localisation de la mission et des cas d’abattements prévus par les textes)

Entreprise:
Caring for the world, one person at a time has inspired and united the people of Johnson and Johnson for over 130 years. We embrace research and science: bringing innovative ideas, products and services to advance the health and well-being of people. With $81.6 billion in 2018 sales, our company is the world's most comprehensive and broadly-based manufacturer of health care products, and provider of related services for the consumer, pharmaceutical and medical devices markets. There are +250 J&J operating companies employing over 125,000 people, with products touching the lives of over a billion people every day, throughout the world. If you have the talent and desire to touch the world, J&J has the career opportunities to help make it happen. The Research & Development department of Janssen Pharmaceutica is based in Beerse (Belgium).

Poste et missions

POSITION SUMMARY:

The in vivo team within therapeutic area Oncology conducts experiments to test the effectiveness of new drugs in tumor models in rodents. To strengthen that team, we are looking for a biotechnician. She/he will work closely with the Animal Welfare team to conduct the experiments under the applicable ethical guidelines and husbandry & welfare regulations.

ESSENTIAL FUNCTIONS:

• Experiments in animals are executed conform internal and external guidelines:
- Compliance with guidelines on health & safety, animal ethics, laboratory animal legislation, quality, data integrity, training plans, time registration, standard operating procedures and work instructions is essential

• Be a role model in the daily care (welfare, health, hygiene) of rodents:
- order and register laboratory animals in Tick@Lab
- daily monitoring of the health of the animal
- know and apply the correct housing (cage size, cage enrichment) conditions
- daily control of environmental parameters (temperature, relative humidity, light, sound)
- assess and register pain levels (P-level)
- report and register non-conformities/observations/injured/sick animals to the PI and veterinarian
- provide care and/or mediation as prescribed by the treating veterinarian
- make 3R suggestions - refinement, reduction, replacement of animal models
- (pro)active cooperation in or with members of the Animal Welfare Body

• Execution of in vivo studies:
- assist in the creation of scientific experiments and development of methodologies
- perform the assigned experiments according protocol
- identification of animals (microchip, tattoo)
- dosing test substances (subcutaneous, intramuscular, oral, intravenous, intraperitoneal)
- application of anesthesia and euthanasia of rodents
- collection of urine and blood samples (orbital, sublingual, tail or other veins)
- assisting in diagnostic autopsy, dissection, surgery and/or special care procedures
- inject tumor cells and measure tumor growth
- knowledge of aseptic work instructions

• Reporting:
- records all information obtained in the experiments according to existing practices and forms
- knowledge and application of specific software m.b.t. capture scientific data
- ensures that documents and data are well preserved
- summarizes data and helps in decision making
- prepares/writes technical reports and other documents
- writes methodologies for internal and/or external use
- uses scientific literature in function of own experiments

• Contribute to efficient vivarium operations:
- correct use and maintenance of the laboratory equipment and computerized systems
- performs calibrations and quality checks
- use and maintenance of IVC (individually ventilated) cages
- order products and equipment through the appropriate processes
- follow-up on technical interventions
- suggest and introduce innovations in the daily processes
- flexibility in terms of working hours (late night dosing, weekend shifts)

COMPETENCIES

Required Technical Knowledge and Skills:
- Handling of laboratory animals (rodents)
- Experience in rodent surgery is a very important plus
- Experience with Microsoft Office applications (Outlook, Word, Excel, PowerPoint)
- Good knowledge of the English language (read, write and speak)
- Able to strictly follow the SOP’s and other guidelines
- Accurate and reliable
- Flexible and able to deal with change
- Able to work independently and in a team
- Good communication skills

Special Training or Certification:
- Laboratory animal science training for scientists, FELASA category B or C is required